What are H2 Blockers and GERD

Many of us run to the pharmacy as soon as we feel any kind of heartburn. When we get to the pharmacy, we're bombarded by different remedies.  One type of remedy we can take are called H2 Blockers.

I thought maybe you'd like some more information on these drugs:

Examples of H2 Blockers

Generic Name	Brand Name
cimetidine	Tagamet
famotidine	Pepcid
nizatidine	Axid
ranitidine	Zantac

H2 blockers (also sometimes referred to as acid reducers or H2 receptor antagonists) are available in nonprescription and prescription forms. Prescription forms are stronger than the nonprescription forms.
H2 blockers are usually taken by mouth, although some can also be given as an injection. Two doses (morning and evening) are generally recommended to control both daytime and nighttime symptoms. Doctors sometimes recommend a single dose, taken at bedtime, for people who have difficulty remembering to take their medicines.

How It Works

H2 blockers reduce the production of stomach acid. This makes the stomach juices less acidic so that any stomach juice that gets into the esophagus is less irritating. This relieves symptoms and allows the esophagus to heal.

Why It Is Used

H2 blockers are used to treat the symptoms of gastroesophageal reflux disease (GERD). They may be prescribed for your symptoms without any diagnostic testing if your symptoms point to GERD.

• H2 blockers may be used together with antacids.
• Nonprescription H2 blockers may be used for up to 2 weeks for short-term symptom relief. But if you have been using nonprescription medicines to treat your symptoms for longer than 2 weeks, talk to your doctor. If you have GERD, the stomach acid could be causing damage to your esophagus. Your doctor can help you find the right treatment.
• H2 blockers may be used on a long-term basis to relieve persistent GERD symptoms.

How Well It Works

All of the H2 blockers in this class are about equally effective.
H2 blockers heal the damage done to the esophagus by GERD (esophagitis) in about 5 out of 10 people.

H2 blockers also work to help symptoms of GERD. But the number of people who take H2 blockers and who have no GERD symptoms is usually less than 5 out of 10 people. That means that of the people taking H2 blockers, more than 5 out of 10 still have some GERD symptoms.

Side Effects

H2 blockers have been in use since the late 1960s. H2 blockers are well studied and are considered very safe.
Minimal side effects occur with use of H2 blockers. Side effects may include:

• Headache.
• Dizziness.
• Diarrhea.
• Constipation.
• Nausea.
• Vomiting.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)